Search results for " Poly-L-Lactic acid"

showing 2 items of 2 documents

Poly-l-Lactic Acid Nanofiber-Polyamidoamine Hydrogel Composites: Preparation, Properties, and Preliminary Evaluation as Scaffolds for Human Pluripote…

2016

Electrospun poly-l-lactic acid (PLLA) nanofiber mats carrying surface amine groups, previously introduced by nitrogen atmospheric pressure nonequilibrium plasma, are embedded into aqueous solutions of oligomeric acrylamide-end capped AGMA1, a biocompatible polyamidoamine with arg-gly-asp (RGD)-reminiscent repeating units. The resultant mixture is finally cured giving PLLA-AGMA1 hydrogel composites that absorb large amounts of water and, in the swollen state, are translucent, soft, and pliable, yet as strong as the parent PLLA mat. They do not split apart from each other when swollen in water and remain highly flexible and resistant, since the hydrogel portion is covalently grafted onto the …

Materials Chemistry2506 Metals and AlloysPluripotent Stem CellsAgmatinePolymers and PlasticsDouble bondpolyamidoaminesPolyestersCell Culture TechniquesNanofibersBioengineering02 engineering and technology010402 general chemistry01 natural sciencesBiomaterialsPolyamidoaminePolyaminesMaterials ChemistryHydrogel compositehuman pluripotent stem cellHumansatmospheric pressure nonequilibrium plasmaInduced pluripotent stem cellatmospheric pressure nonequilibrium plasma; electrospun poly-l-lactic nanofibers; human pluripotent stem cells; poly-l-lactic acid-AGMA1 hydrogel composites; polyamidoamines; biotechnology; bioengineering; biomaterials; polymers and plastics; materials chemistry2506 metals and aloyschemistry.chemical_classificationAddition reactionPolymers and PlasticAqueous solutionTissue ScaffoldsHydrogels021001 nanoscience & nanotechnologyBiomaterial0104 chemical sciencesChemical engineeringchemistryCovalent bondNanofiberelectrospun poly-l-lactic nanofiberpoly-l-lactic acid-AGMA1 hydrogel compositeAmine gas treating0210 nano-technologyBiotechnology
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A COMPOSITE PLLA SCAFFOLD FOR REGENERATION OF COMPLEX TISSUES

2010

A composite biodegradable scaffold incorporating an integrated network of synthetic blood vessels was designed and prepared, in line with the requirements of a scaffold effectively supporting the regeneration of highly vascularized tissues. In other words, this composite scaffold should allow the regeneration of complex injured tissue (e.g. dermis) and, at the same time, favour the development of a vascular network on its inner, i.e. a 3D polymeric scaffolds embedding synthetic blood vessel-like structures for nutrient supply and metabolite removal. PLLA assures a high degree of biocompatibility and a low level of inflammation response upon implantation, while the embedded tubular vessel-li…

ScaffoldSettore ING-IND/24 - Principi Di Ingegneria ChimicaSettore ING-IND/26 - Teoria Dello Sviluppo Dei Processi ChimiciMaterials scienceBiocompatibilityRegeneration (biology)Composite numberPlla scaffoldPhase separation tissue engineering Poly-L-Lactic acidmedicine.anatomical_structureDermisTissue engineeringBiodegradable scaffoldSettore BIO/10 - BiochimicaTissue engineering vasculogenesis Poly-lactic acidmedicineGeneral Materials ScienceBiomedical engineering
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